IJE TRANSACTIONS A: Basics Vol. 31, No. 4 (April 2018) 673-678    Article in Press

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R. Ghasemiasl, R. Ostadhossein, M. A. Javadi and S. Hoseinzadeh
( Received: September 23, 2017 – Accepted in Revised Form: November 30, 2017 )

Abstract    Coarctation of the aorta is one of the five main congenital cardiovascular failures, accounting for 6–8 percent of these failures. This research aimed to simulate the blood flow of a seventeen-year-old male teen with a mild coarctation at one-third of his aorta's descending branch. The simulation was performed by extracting the domain and the input pulsatile velocity signal as the boundary condition at the aorta entrance using magnetic resonance angiography (MRA) and the finite volume method (FVM), as well as a large eddy simulation (LES) turbulence model. The results were validated by comparing the blood flow static pressure from the numerical simulation to a clinical measurement available in the literature. The Inclusion of the turbulence model in the solution resulted in a static pressure for the heart’s normal function at the coarctation that agreed very well with the clinical measurement; the difference was just 0.39 mmHg. Therefore, the study confirmed the validity of the simulation results, the assumption that a turbulence regime exists inside an aorta with a coarctation, and the efficiency of the LES turbulence model for simulating cardiovascular flows.


Keywords    Aortic Coarctation; Finite Volume Method; Magnetic Resonance Angiography; Large Eddy Simulation Model; Windkessel Model


چکیده    انسداد مادرزادي آئورت يكي از پنج نقص قلبي مادرزادي است كه 6 تا 8 درصد كليه نقايص قلبي-عروقي را شامل مي شود. هدف از اين تحقيق شبيه سازي جريان خون در يك نوجوان هفده ساله مذكر به همراه يك گرفتگيملايم در يك سوم شاخه صعودي آئورت مي باشد. شبيه سازي مورد نظر از طريق استخراج مدل و سيگنال سرعت نوساني ورودي به عنوان شرط مرزي مسئله در ورودي آئورت با استفاده از آنژيوگرافي رزونانس مغناطيسي و روش حجم محدود به همراه مدل شبيه ساز آشفتگي گردابه هاي بزرگ انجام پذيرفته است. نتايج اين پژوهش از طريق مقايسه فشار استاتيك به دست آمده از شبيه سازي عددي و اندازه گيري باليني موجود پيشينه پژوهش به انجام رسيده است. نتايج حاصل از شبيه سازي فشار استاتيكي به همراه به كارگيري مدل آشفتگي مذكور انطباق بسيار خوبي را با اندازه گيري باليني نشان مي دهد. ميزان اختلاف تنها 39/0 ميلي متر جيوه مي باشد. مقايسه مقادير حاصل از شبيه سازي عددي و اندازه گيري باليني فرض وجود يك جريان آشفته در موضع انسداد و كارايي مدل آشفتگي شبيه ساز گردابه هاي بزرگ را در شبيه سازي جريان هاي قلبي عروقي تاييد مي نمايد.


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